VTE Prophylaxis in Critical Care: A Comprehensive Clinical Guideline

Evidence-based guideline for venous thromboembolism prevention in critically ill patients, including pharmacologic and mechanical prophylaxis, special populations, and monitoring.

4 articles Updated Mar 2026

VTE Prophylaxis in Critical Care — Part 4: Special ICU Populations, HIT & Quality Metrics

VTE prophylaxis in traumatic brain injury, spinal cord injury, neurosurgery, burns, stroke, cardiac surgery, orthopedic trauma, ECMO, thrombocytopenia, active bleeding, pregnancy, and obesity; HIT recognition and alternative anticoagulants; quality metrics and compliance monitoring.

VTE Prophylaxis in Critical Care — Part 3: Mechanical Prophylaxis, IVC Filters & Diagnosis of ICU-Acquired VTE

Evidence for intermittent pneumatic compression and graduated compression stockings, IVC filter indications and complications, screening ultrasound protocols, CTPA decision-making, and transition from prophylaxis to treatment.

VTE Prophylaxis in Critical Care — Part 2: Pharmacologic Prophylaxis

Complete dosing tables for LMWH, UFH, and fondaparinux in ICU patients, renal and obesity dose adjustments, anti-Xa monitoring, key trial evidence (PROTECT, PREVENT, INSPIRATION), and duration of prophylaxis.

VTE Prophylaxis in Critical Care — Part 1: Epidemiology, Risk Factors & Risk Assessment

Incidence and pathophysiology of VTE in critically ill patients, comprehensive ICU risk factors, and complete risk assessment scoring systems including Padua Prediction Score, Caprini Score, and IMPROVE Score.