ICU Clinical Guidelines

Comprehensive, evidence-based clinical guidelines for intensive care practice — synthesized from multiple professional society recommendations covering sepsis, ventilation, sedation, infection prevention, nutrition, hemostasis, renal support, post-arrest care, and transfusion medicine.

12 articles Updated Mar 2026

Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock in Children 2026

Complete clinical reference for the 2026 Surviving Sepsis Campaign pediatric guidelines — 61 evidence-based recommendations covering recognition, antimicrobial therapy, fluid therapy, hemodynamic management, vasoactive medications, ventilation, corticosteroids, metabolic management, blood products, renal replacement therapy, ECMO, immune therapies, long-term follow-up, and prophylaxis in pediatric sepsis and septic shock.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Complete clinical reference for the 2026 Surviving Sepsis Campaign international guidelines — 129 evidence-based recommendations covering screening, antimicrobial therapy, hemodynamic management, respiratory support, adjunctive therapies, goals of care, transitions, and long-term outcomes in adult sepsis and septic shock.

VTE Prophylaxis in Critical Care: A Comprehensive Clinical Guideline

Evidence-based guideline for venous thromboembolism prevention in critically ill patients, including pharmacologic and mechanical prophylaxis, special populations, and monitoring.

Ventilator-Associated Pneumonia: A Comprehensive Prevention and Management Guideline

Evidence-based guideline for VAP prevention bundles, diagnostic approaches, empiric and targeted antimicrobial therapy, and surveillance in mechanically ventilated patients.

Transfusion Practice in Critical Care: A Comprehensive Clinical Guideline

Evidence-based guideline for red cell, platelet, plasma, and cryoprecipitate transfusion, massive transfusion protocols, transfusion reactions, and patient blood management in the critically ill.

Sepsis and Septic Shock: A Comprehensive Clinical Management Guideline

Evidence-based guideline for screening, resuscitation, hemodynamic management, antimicrobial therapy, and organ support in sepsis and septic shock, synthesized from international critical care recommendations.

Sedation, Analgesia, Delirium, and Mobility in Critical Care: A Comprehensive Clinical Guideline

Evidence-based guideline for pain assessment, sedation management, delirium prevention and treatment, early mobility, and sleep promotion in the ICU — the PADIS/ABCDEF bundle approach.

Post-Cardiac Arrest Care and Targeted Temperature Management: A Comprehensive Clinical Guideline

Evidence-based guideline for post-ROSC management, targeted temperature management, neuroprognostication, seizure management, and long-term recovery after cardiac arrest.

Nutrition in Critical Illness: A Comprehensive Clinical Guideline

Evidence-based guideline for nutritional assessment, enteral and parenteral nutrition, micronutrient supplementation, and special population management in the critically ill patient.

Mechanical Ventilation and ARDS Management: A Comprehensive Clinical Guideline

Evidence-based guideline for lung-protective ventilation, prone positioning, PEEP optimization, rescue therapies, and ventilator liberation in acute respiratory distress syndrome.