Vascular Access Device Types: A Complete Comparison Guide

Complete comparison of all vascular access device types: PIV, midline, PICC, CVC, tunneled catheter, port, hemodialysis catheter, IO, and arterial line — with a clinical selection guide.

guideFeb 2026Vascular Access Devices

Vascular Access Device Types: A Complete Comparison Guide

Choosing the right vascular access device requires understanding the clinical characteristics, appropriate indications, and limitations of each device type. This guide provides a structured comparison of all major vascular access device types used in clinical practice.

Parent guide: Vascular Access: Complete Clinical Reference


The Complete VAD Spectrum

Peripheral IV Catheter (PIV)

Description: Short catheter (approximately 1.25–2.5 cm) inserted into a peripheral vein (dorsum of hand, forearm, antecubital fossa). The most common invasive procedure in healthcare.

FeatureDetail
Tip locationPeripheral vein (hand, forearm, antecubital)
Dwell time72–96 hours; change per institutional protocol
Lumen countSingle
Osmolarity limit<600 mOsm/L (strongly preferred)
VesicantsNot appropriate
Blood drawsLimited; not standard practice in most settings
PlacementAny trained RN or qualified clinician
Infection riskLow (no CLABSI risk; phlebitis and infiltration risk)

Appropriate for: Most short-term IV medications, IV fluids, electrolyte replacement, single-dose medications, blood products (with appropriate gauge).

Not appropriate for: Therapy requiring osmolarity >600 mOsm/L, vesicants, TPN (standard), dwell >96 hours, or frequent blood draws.


Midline Catheter

Description: Longer catheter (approximately 8–25 cm) inserted via upper arm peripheral vein, with the tip terminating in the axillary or subclavian vein — below the thoracic cavity. Not a central venous access device.

FeatureDetail
Tip locationAxillary or subclavian vein (peripheral)
Dwell time1–4 weeks
Lumen countSingle or double
Osmolarity limit<600–800 mOsm/L
VesicantsNot appropriate (peripheral tip)
Blood drawsPer institutional policy; some midlines acceptable
PlacementCredentialed RN or APRN with US guidance
Infection riskLow-moderate; no CLABSI designation (peripheral device)

Appropriate for: IV therapy 1–4 weeks not requiring central access (moderate-duration antibiotics, fluids, non-vesicant medications), patients with difficult peripheral access needing reliable access without PICC indication.

Not appropriate for: Central-access drugs (vesicants, TPN >900 mOsm/L), therapy >4 weeks, blood sampling in most settings.


PICC Line (Peripherally Inserted Central Catheter)

Description: Long catheter inserted via upper arm peripheral vein and advanced until the tip rests in the lower SVC at the cavoatrial junction (CAJ). Central access via peripheral insertion approach.

FeatureDetail
Tip locationLower SVC / cavoatrial junction
Dwell timeWeeks to months
Lumen countSingle, double, or triple
OsmolarityCentral tip — can accommodate >900 mOsm/L
VesicantsYes (central tip)
Blood drawsYes (per protocol)
PlacementCredentialed RN (VAT), APRN, MD with US guidance
Infection riskLow-moderate; CLABSI designation applies

Appropriate for: IV therapy ≥5–7 days requiring central access, OPAT, TPN, chemotherapy, vesicants, multi-lumen needs. See PICC Line Indications.

Not appropriate for: ESRD patients (vessel preservation), short-term therapy (<5 days) with adequate peripheral access, patients with known DVT in target vein.


Non-Tunneled Central Venous Catheter (CVC)

Description: Catheter inserted directly into the IJ, subclavian, or femoral vein, with tip in the SVC or IVC. Short-term acute care device.

FeatureDetail
Tip locationLower SVC (IJ/subclavian) or IVC (femoral)
Dwell timeDays to approximately 2 weeks
Lumen countSingle to quad-lumen
OsmolarityCentral tip — all infusates
Insertion riskPneumothorax, hemothorax, arterial puncture
PlacementMD, PA, NP with privileges
Infection riskModerate; CLABSI risk varies by site (subclavian < IJ < femoral)

Appropriate for: ICU hemodynamic monitoring, emergency central access, CVP monitoring, situations requiring immediate central access.

Not appropriate for: Stable patients requiring long-term therapy where PICC or tunneled catheter is safer and more comfortable.


Tunneled Central Venous Catheter (Hickman, Broviac, Groshong)

Description: Surgically placed catheter tunneled subcutaneously from entry vein to separate skin exit site. Dacron cuff promotes tissue ingrowth for anchorage and infection barrier.

FeatureDetail
Tip locationLower SVC
Dwell timeMonths to years
Lumen countSingle to triple
Exit siteExternal; requires dressing
PlacementInterventional radiology or surgery
Infection riskLower than non-tunneled for comparable dwell

Appropriate for: Long-term home IV therapy, stem cell transplantation, home TPN, chronic IV access needs where port is not feasible.


Implanted Vascular Access Port

Description: Subcutaneous reservoir connected to a central venous catheter. No external components between uses; accessed via non-coring Huber needle through skin.

FeatureDetail
Tip locationLower SVC
Dwell timeYears (device lifespan 10+ years)
External componentNone between accesses
Access requirementHuber needle + ANTT
PlacementIR or surgery
Infection riskLowest of all CVADs (per comparable dwell period)

Appropriate for: Intermittent chemotherapy, long-term recurrent IV access, patients for whom body image/daily life impact is a priority.


Tunneled Hemodialysis Catheter

Description: Large-bore (12–14 Fr) dual-lumen tunneled catheter designed for high-flow dialysis access. Distinct from standard CVCs.

FeatureDetail
PurposeHemodialysis (300–450 mL/min flow rates)
Tip locationRight atrium or IVC/RA junction
Flow rateHigh-flow (dialysis-specific)
Infection riskHighest of all CVAD types per catheter-day

Appropriate for: Bridge hemodialysis access while waiting for AV fistula maturation; patients not suitable for surgical access.


Intraosseous (IO) Catheter

Description: Needle inserted into the bone marrow cavity (tibia, sternum, or humerus) for emergency vascular access.

FeatureDetail
Dwell time<24 hours
PurposeEmergency resuscitation when IV unavailable
Flow rateAdequate for emergency medications
ConversionMust convert to IV access ASAP

Arterial Line

Description: Catheter in the arterial system (radial artery preferred) for continuous hemodynamic monitoring and serial blood gas sampling.

FeatureDetail
PurposeBlood pressure monitoring; ABG sampling
MedicationsLimited; arterial drug delivery is hazardous
PlacementMD, PA, NP in most settings
Infection riskLower than CVCs; arterial infection is serious

Comparison Summary Table

DeviceTipDwellVesicantsTPNCLABSI Risk
PIVPeripheral72–96hNoNoNone
MidlinePeripheral1–4 wkNoNoNone
PICCCentral (SVC)Wk–monthsYesYesLow–moderate
Non-tunneled CVCCentralDaysYesYesModerate
Tunneled CVCCentralMo–yearsYesYesLow
Implanted PortCentralYearsYesYesLowest
HD CatheterCentral/RAMoNoNoHighest
IOIntraosseous<24hEmergencyNoMinimal
Arterial lineArterialDaysNoNoLow


References

  1. Gorski LA, et al. (2021). INS Infusion Therapy Standards of Practice. J Infus Nurs, 44(Suppl 1).
  2. Chopra V, et al. (2015). MAGIC criteria. Ann Intern Med, 163(6 Suppl).