Acute Coronary Syndromes: A Comprehensive Emergency Management Guideline

Evidence-based guideline for evaluation, risk stratification, and management of STEMI, NSTEMI, and unstable angina in the emergency department.

5 articles • Updated Mar 2026

Acute Coronary Syndromes — Part 5: Post-ACS Care, Secondary Prevention & Quality Metrics

Long-term antiplatelet therapy and DAPT duration, statin therapy, ACE inhibitor/ARB, beta-blocker, aldosterone antagonists, cardiac rehabilitation, lifestyle modification, and quality metrics.

guidelines•Mar 2026•guidelines

Acute Coronary Syndromes — Part 4: NSTEMI/UA Management, Special Populations & Disposition

Early invasive vs conservative strategy, timing of angiography, antiplatelet and anticoagulation for NSTEMI, special populations (women, elderly, diabetes, CKD, cocaine), arrhythmias, and chest pain disposition.

guidelines•Mar 2026•guidelines

Acute Coronary Syndromes — Part 3: STEMI Management — Reperfusion, Pharmacotherapy & Complications

Systems of care, primary PCI, fibrinolytic therapy with dosing, pharmacoinvasive strategy, dual antiplatelet therapy, anticoagulation, adjunctive therapy, cardiogenic shock, and mechanical complications.

guidelines•Mar 2026•guidelines

Acute Coronary Syndromes — Part 2: Cardiac Biomarkers & Risk Stratification

Troponin biology, high-sensitivity troponin algorithms (0/1h and 0/3h), HEART score, TIMI risk scores, GRACE score, HEART Pathway, and chest pain observation pathways.

guidelines•Mar 2026•guidelines

Acute Coronary Syndromes — Part 1: Definitions, Pathophysiology & Initial Evaluation

ACS spectrum definitions, Fourth Universal Definition of MI (Types 1-5), pathophysiology, initial ED evaluation, 12-lead ECG interpretation, STEMI criteria by territory, STEMI equivalents, and right ventricular MI.

guidelines•Mar 2026•guidelines