SSC 2026 Guidelines now available — 129 adult & 61 pediatric recommendations View guidelines →
Evidence-based guideline for AKI staging, prevention, conservative management, renal replacement therapy modalities, CRRT prescription, and special populations in the critically ill.
Sepsis-associated AKI, cardiac surgery-associated AKI, contrast-associated AKI, hepatorenal syndrome, rhabdomyolysis, tumor lysis syndrome, AKI in pregnancy, long-term outcomes, CKD progression, nephrology referral criteria, and quality metrics.
RRT modalities comparison (IHD, CRRT, SLED/PIRRT), timing evidence (STARRT-AKI, AKIKI, IDEAL-ICU, ELAIN), CRRT prescription and dose, citrate and heparin anticoagulation protocols, vascular access, troubleshooting, and discontinuation criteria.
Fluid management, hyperkalemia emergency algorithm, electrolyte and acid-base management, diuretic therapy including furosemide stress test, drug dosing in AKI, and nutritional considerations.
Pre-renal, intrinsic, and post-renal AKI causes; diagnostic workup including urinalysis, FENa, FEUrea, and imaging; prevention strategies; nephrotoxin avoidance; contrast-associated AKI evidence; drug dose adjustment table.
KDIGO AKI definition and staging criteria, RIFLE and AKIN historical comparison, novel biomarkers (NGAL, KIM-1, NephroCheck), subclinical AKI, ICU epidemiology, and outcomes by stage.
Establishes standards for hemodialysis vascular access device selection, vessel health and preservation, access hierarchy, infection prevention, hub care, AVF/AVG cannulation, catheter locking solutions, and patient education for patients receiving or anticipated to receive hemodialysis.