SSC 2026 Guidelines now available — 129 adult & 61 pediatric recommendations View guidelines →
Complete clinical reference for the 2026 Surviving Sepsis Campaign international guidelines — 129 evidence-based recommendations covering screening, antimicrobial therapy, hemodynamic management, respiratory support, adjunctive therapies, goals of care, transitions, and long-term outcomes in adult sepsis and septic shock.
Surviving Sepsis Campaign 2026 recommendations for performance improvement programs, code sepsis protocols, prehospital and in-hospital screening, biomarkers, blood cultures, lactate measurement, initial fluid resuscitation, vasopressor timing, peripheral vasopressor initiation, MAP targets, and ICU admission.
Evidence-based guideline for recognition, decontamination, specific antidote therapy, and enhanced elimination in acute poisoning and overdose presentations.
Evidence-based guideline for pediatric resuscitation, respiratory emergencies, sepsis, febrile infant evaluation, seizures, dehydration, and common surgical emergencies in children.
Comprehensive, evidence-based clinical guidelines for emergency medicine practice — synthesized from multiple professional society recommendations covering cardiac emergencies, stroke, trauma, toxicology, airway management, pediatrics, and procedural care.
Evidence-based guideline for multimodal analgesia, opioid stewardship, ultrasound-guided regional anesthesia, and procedural sedation agents and protocols in the ED.
One pill can kill agents, weight-based pediatric antidote dosing, comprehensive antidote dosing reference table, toxicologic cardiac arrest management by agent, alcohol withdrawal protocols, synthetic cannabinoids, novel psychoactive substances, and poison center consultation guidance.
Complete management of methanol and ethylene glycol poisoning (fomepizole, hemodialysis), carbon monoxide, cyanide, organophosphates and nerve agents, iron poisoning, caustic ingestions, local anesthetic systemic toxicity (LAST), sympathomimetic toxicity, and enhanced elimination techniques including urinary alkalinization and EXTRIP hemodialysis indications.
Renal colic, fractures, headache, sickle cell crisis, burns, pediatric procedural pain, geriatric considerations, discharge multimodal prescribing, opioid alternatives, PDMP requirements, and quality metrics.
Complete management of TCA poisoning (sodium bicarbonate protocol), calcium channel blocker overdose (high-dose insulin), beta-blocker toxicity, digoxin poisoning (DigiFab), serotonin syndrome, neuroleptic malignant syndrome, lithium toxicity, and antipsychotic overdose.
LET gel, EMLA cream, lidocaine buffering, hematoma block, intra-articular injection, sedation continuum, pre-sedation assessment, sedation agents with complete dosing, ketamine considerations, modified Aldrete score, and recovery criteria.
Complete management of acetaminophen overdose (NAC protocols), salicylate poisoning (alkalinization, hemodialysis), opioid overdose (naloxone titration), benzodiazepine reversal (flumazenil), and sedative-hypnotic poisonings.
Opioid dosing tables, equianalgesic conversions, intranasal fentanyl, opioid stewardship, risk assessment tools, ultrasound-guided nerve blocks, local anesthetic agents, and LAST protocol.
Initial approach to the poisoned patient including toxidrome recognition, diagnostic workup, toxicology screen interpretation, and gastrointestinal decontamination strategies including activated charcoal, whole bowel irrigation, gastric lavage, and multi-dose activated charcoal.
Pain assessment scales (NRS, VAS, FACES, FLACC, PAINAD), oligoanalgesia prevention, and first-line non-opioid analgesics including acetaminophen, NSAIDs, subdissociative ketamine, IV lidocaine, trigger point injections, and nitrous oxide.