Traumatic Brain Injury: A Comprehensive Clinical Management Guideline
Evidence-based guideline for classification, imaging decisions, ICP management, surgical indications, and outcome prediction in traumatic brain injury across all severity levels.
ed
Trauma Primary and Secondary Survey: A Comprehensive Clinical Guideline
Evidence-based guideline for systematic trauma evaluation including ABCDE primary survey, hemorrhagic shock management, damage control resuscitation, injury-specific assessment, and special populations.
Toxicology and Overdose Management: A Comprehensive Emergency Guideline
Evidence-based guideline for recognition, decontamination, specific antidote therapy, and enhanced elimination in acute poisoning and overdose presentations.
Post-Cardiac Arrest Care and Targeted Temperature Management: A Comprehensive Clinical Guideline
Evidence-based guideline for post-ROSC management, targeted temperature management, neuroprognostication, seizure management, and long-term recovery after cardiac arrest.
Pediatric Emergencies: A Comprehensive Clinical Guideline
Evidence-based guideline for pediatric resuscitation, respiratory emergencies, sepsis, febrile infant evaluation, seizures, dehydration, and common surgical emergencies in children.
Emergency Department Clinical Guidelines
Comprehensive, evidence-based clinical guidelines for emergency medicine practice — synthesized from multiple professional society recommendations covering cardiac emergencies, stroke, trauma, toxicology, airway management, pediatrics, and procedural care.
Advanced Cardiac Life Support and Cardiac Arrest Management: A Comprehensive Clinical Guideline
Evidence-based guideline for cardiac arrest algorithms, defibrillation, ACLS medications, arrhythmia management, special circumstances, and post-arrest care.
Acute Stroke Management: A Comprehensive Emergency Guideline
Evidence-based guideline for recognition, evaluation, thrombolysis, thrombectomy, and management of ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage in the emergency department.
Acute Pain Management and Procedural Sedation in the Emergency Department: A Comprehensive Clinical Guideline
Evidence-based guideline for multimodal analgesia, opioid stewardship, ultrasound-guided regional anesthesia, and procedural sedation agents and protocols in the ED.
Acute Coronary Syndromes: A Comprehensive Emergency Management Guideline
Evidence-based guideline for evaluation, risk stratification, and management of STEMI, NSTEMI, and unstable angina in the emergency department.
Acute Airway Management and Rapid Sequence Intubation: A Comprehensive Clinical Guideline
Evidence-based guideline for airway assessment, preoxygenation, RSI medications, difficult airway algorithms, surgical airway, and scenario-specific airway management.
Acute Abdominal Emergencies: A Comprehensive Clinical Guideline
Evidence-based guideline for evaluation and management of surgical and non-surgical abdominal emergencies including appendicitis, cholecystitis, pancreatitis, bowel obstruction, and mesenteric ischemia.
Traumatic Brain Injury — Part 5: Concussion, Special Populations & Prognosis
Concussion assessment (SCAT6), return-to-play and return-to-learn protocols, post-concussive syndrome, pediatric TBI, geriatric TBI, TBI in pregnancy, IMPACT and CRASH prognostic models, biomarkers (GFAP, UCH-L1, S100B, NSE), and rehabilitation referral criteria.
Trauma Primary and Secondary Survey — Part 5: Special Trauma Populations
Pediatric trauma (vital signs by age, Broselow, non-accidental trauma), geriatric trauma (anticoagulant reversal, occult shock), pregnant trauma (physiologic changes, perimortem C-section), burns (Parkland formula, rule of nines, escharotomy), and penetrating vs blunt selective non-operative management.
Toxicology and Overdose Management — Part 5: Pediatric Poisoning, Antidote Reference Table, Toxicologic Cardiac Arrest & Substance Abuse Emergencies
One pill can kill agents, weight-based pediatric antidote dosing, comprehensive antidote dosing reference table, toxicologic cardiac arrest management by agent, alcohol withdrawal protocols, synthetic cannabinoids, novel psychoactive substances, and poison center consultation guidance.
Pediatric Emergencies — Part 5: Common Surgical Emergencies, Trauma & Neonatal Emergencies
Intussusception, pyloric stenosis, testicular torsion, PECARN head CT and abdominal trauma decision rules, solid organ injury non-operative management, non-accidental trauma screening, neonatal emergencies including hypoglycemia, congenital heart disease with PGE1, hyperbilirubinemia, and a comprehensive pediatric medication dosing reference table.
Acute Stroke Management — Part 5: Subarachnoid Hemorrhage, TIA & Special Populations
SAH presentation, Hunt & Hess scale, WFNS grade, Fisher CT grading, aneurysm management, vasospasm prevention, DCI, TIA evaluation (ABCD2, dual antiplatelet), stroke mimics, posterior circulation, wake-up stroke, pregnancy, and pediatric stroke.
Acute Coronary Syndromes — Part 5: Post-ACS Care, Secondary Prevention & Quality Metrics
Long-term antiplatelet therapy and DAPT duration, statin therapy, ACE inhibitor/ARB, beta-blocker, aldosterone antagonists, cardiac rehabilitation, lifestyle modification, and quality metrics.
ACLS & Cardiac Arrest — Part 5: ECPR, CPR Quality Metrics, Pediatric Considerations & Termination of Resuscitation
Extracorporeal CPR indications and evidence, CPR quality metrics and physiologic targets, pediatric cardiac arrest differences with weight-based dosing, neonatal resuscitation overview, termination of resuscitation criteria, and post-arrest care cross-reference.
Traumatic Brain Injury — Part 4: Specific Injury Types, Herniation & Advanced Monitoring
Epidural hematoma, acute and chronic subdural hematoma, traumatic subarachnoid hemorrhage, diffuse axonal injury, skull fractures, penetrating TBI, cerebral herniation syndromes, and advanced neuromonitoring including PbtO2, cerebral microdialysis, continuous EEG, and transcranial Doppler.
Trauma Primary and Secondary Survey — Part 4: Focused Injury-Specific Assessment
Head injury assessment, cervical spine clearance (Canadian C-Spine Rule, NEXUS), chest injury evaluation, abdominal assessment with AAST organ injury grading (liver, spleen, kidney), pelvic fracture management, extremity vascular injury and compartment syndrome, and spinal injury with TLICS scoring.
Toxicology and Overdose Management — Part 4: Toxic Alcohols, Metals, Organophosphates, Environmental & Chemical Poisonings
Complete management of methanol and ethylene glycol poisoning (fomepizole, hemodialysis), carbon monoxide, cyanide, organophosphates and nerve agents, iron poisoning, caustic ingestions, local anesthetic systemic toxicity (LAST), sympathomimetic toxicity, and enhanced elimination techniques including urinary alkalinization and EXTRIP hemodialysis indications.
Pediatric Emergencies — Part 4: Neurologic, Metabolic & Fluid Emergencies
Febrile seizure evaluation, status epilepticus protocol with stepwise treatment, clinical dehydration assessment, WHO dehydration classification, ORT protocol, IV fluid calculation with Holliday-Segar rule, hyponatremia correction, and pediatric diabetic ketoacidosis management including 2-bag system and cerebral edema monitoring.
Acute Stroke Management — Part 4: Intracerebral Hemorrhage
ICH pathophysiology, ICH Score, hematoma expansion, blood pressure management (INTERACT2, ATACH-2), anticoagulant reversal protocols, surgical intervention criteria (STICH, MISTIE III, ENRICH), and ICP management.
Acute Pain & Procedural Sedation — Part 4: Specific Pain Scenarios, Discharge Management & Quality Metrics
Renal colic, fractures, headache, sickle cell crisis, burns, pediatric procedural pain, geriatric considerations, discharge multimodal prescribing, opioid alternatives, PDMP requirements, and quality metrics.
Acute Coronary Syndromes — Part 4: NSTEMI/UA Management, Special Populations & Disposition
Early invasive vs conservative strategy, timing of angiography, antiplatelet and anticoagulation for NSTEMI, special populations (women, elderly, diabetes, CKD, cocaine), arrhythmias, and chest pain disposition.
Acute Airway Management & RSI — Part 4: Clinical Scenarios & Post-Intubation Management
Scenario-specific airway management for trauma, elevated ICP, status asthmaticus, morbid obesity, pregnancy, pediatric patients, angioedema/anaphylaxis, and burns. Complete post-intubation ventilator settings, sedation/analgesia regimens, extubation criteria, and equipment reference tables by age and weight.
Acute Abdominal Emergencies — Part 4: Perforated Peptic Ulcer, Mesenteric Ischemia, Vascular Emergencies & Special Populations
Comprehensive guide to perforated peptic ulcer with Boey score, mesenteric ischemia types and management, ruptured AAA emergency management, ectopic pregnancy evaluation and treatment, and special populations including pediatric, elderly, immunocompromised, and pregnant patients.
ACLS & Cardiac Arrest — Part 4: Special Circumstances in Cardiac Arrest
Cardiac arrest management in pregnancy, drowning, hypothermia, pulmonary embolism, tension pneumothorax, cardiac tamponade, opioid overdose, hyperkalemia, anaphylaxis, and toxicologic emergencies.
Traumatic Brain Injury — Part 3: ICP Management & Surgical Indications
ICP monitoring indications, ICP and CPP targets, complete tiered ICP management protocol with dosing, hyperosmolar therapy, EVD drainage, decompressive craniectomy (DECRA, RESCUEicp), barbiturate coma, and surgical indications for epidural hematoma, subdural hematoma, depressed skull fracture, and posterior fossa lesions.
Trauma Primary and Secondary Survey — Part 3: Damage Control Resuscitation & Transfusion
Permissive hypotension, massive transfusion protocol with 1:1:1 ratio, tranexamic acid (CRASH-2), crystalloid limitation, hypothermia prevention, acidosis correction, viscoelastic hemostatic assays, and whole blood resuscitation.
Toxicology and Overdose Management — Part 3: Cardiovascular Drug, Antidepressant & Psychotropic Poisonings
Complete management of TCA poisoning (sodium bicarbonate protocol), calcium channel blocker overdose (high-dose insulin), beta-blocker toxicity, digoxin poisoning (DigiFab), serotonin syndrome, neuroleptic malignant syndrome, lithium toxicity, and antipsychotic overdose.
Pediatric Emergencies — Part 3: Pediatric Sepsis & Febrile Infant Evaluation
Pediatric sepsis recognition with age-specific SIRS criteria, sepsis resuscitation protocol, vasopressor selection, antibiotic guidance, febrile infant risk stratification by age, Rochester-Philadelphia-Boston criteria comparison, PECARN febrile infant rule, and neonatal CSF interpretation.
Acute Stroke Management — Part 3: Endovascular Thrombectomy & Blood Pressure Management
EVT indications, landmark trials, extended window therapy (DAWN, DEFUSE-3), anesthesia considerations, and comprehensive blood pressure management with antihypertensive dosing tables.
Acute Pain & Procedural Sedation — Part 3: Topical & Local Anesthesia and Procedural Sedation
LET gel, EMLA cream, lidocaine buffering, hematoma block, intra-articular injection, sedation continuum, pre-sedation assessment, sedation agents with complete dosing, ketamine considerations, modified Aldrete score, and recovery criteria.
Acute Coronary Syndromes — Part 3: STEMI Management — Reperfusion, Pharmacotherapy & Complications
Systems of care, primary PCI, fibrinolytic therapy with dosing, pharmacoinvasive strategy, dual antiplatelet therapy, anticoagulation, adjunctive therapy, cardiogenic shock, and mechanical complications.
Acute Airway Management & RSI — Part 3: Difficult Airway Management & Surgical Airway
Failed first attempt optimization, video laryngoscopy types and evidence, bougie technique, supraglottic airways with sizing tables, intubating through SGA, front-of-neck access (FONA), surgical cricothyrotomy (scalpel-bougie-tube), needle cricothyrotomy, and the complete difficult airway algorithm.
Acute Abdominal Emergencies — Part 3: Small Bowel Obstruction, Large Bowel Obstruction & Diverticulitis
Comprehensive guide to adhesive small bowel obstruction with CT findings, conservative management, water-soluble contrast challenge, and surgical indications; large bowel obstruction including volvulus and Ogilvie syndrome; and diverticulitis with Hinchey classification, DIABOLO trial evidence, and surgical decision-making.
ACLS & Cardiac Arrest — Part 3: Tachyarrhythmia & Bradyarrhythmia Management
Narrow and wide complex tachycardia algorithms, synchronized cardioversion energy levels, SVT management with adenosine, atrial fibrillation rate and rhythm control, bradycardia algorithm, atropine, transcutaneous pacing, and vasopressor infusions.
Traumatic Brain Injury — Part 2: Initial Management & Resuscitation
Airway management and RSI in TBI, oxygenation and ventilation targets, blood pressure management, seizure prophylaxis, coagulopathy reversal, TXA (CRASH-3), and cerebral herniation emergency management.
Trauma Primary and Secondary Survey — Part 2: Adjuncts to Primary Survey, Secondary Survey & Hemorrhagic Shock
Extended FAST technique, chest and pelvis radiography, Foley and NG tube placement, complete head-to-toe secondary survey, AMPLE history, and hemorrhagic shock classification with Classes I-IV.
Toxicology and Overdose Management — Part 2: Analgesic, Opioid, Benzodiazepine & Sedative Poisonings
Complete management of acetaminophen overdose (NAC protocols), salicylate poisoning (alkalinization, hemodialysis), opioid overdose (naloxone titration), benzodiazepine reversal (flumazenil), and sedative-hypnotic poisonings.
Pediatric Emergencies — Part 2: Pediatric Respiratory Emergencies
Croup scoring and management, bronchiolitis evaluation and supportive care, acute asthma severity classification and stepwise treatment, anaphylaxis recognition and epinephrine dosing, and foreign body aspiration management.
Acute Stroke Management — Part 2: Intravenous Thrombolysis
Alteplase and tenecteplase dosing, complete inclusion/exclusion criteria for 0-3h and 3-4.5h windows, blood pressure management peri-thrombolysis, orolingual angioedema, and hemorrhagic transformation.
Acute Pain & Procedural Sedation — Part 2: Opioid Analgesics & Regional Anesthesia in the ED
Opioid dosing tables, equianalgesic conversions, intranasal fentanyl, opioid stewardship, risk assessment tools, ultrasound-guided nerve blocks, local anesthetic agents, and LAST protocol.
Acute Coronary Syndromes — Part 2: Cardiac Biomarkers & Risk Stratification
Troponin biology, high-sensitivity troponin algorithms (0/1h and 0/3h), HEART score, TIMI risk scores, GRACE score, HEART Pathway, and chest pain observation pathways.
Acute Airway Management & RSI — Part 2: RSI Protocol & Medications
Complete RSI protocol including preparation, pretreatment agents, induction agents with dosing tables, neuromuscular blocking agents with contraindications and reversal, paralysis verification, post-intubation sedation, confirmation of intubation, awake intubation, and drug-assisted intubation without paralysis.
Acute Abdominal Emergencies — Part 2: Acute Cholecystitis, Cholangitis & Acute Pancreatitis
Comprehensive guide to acute cholecystitis with Tokyo Guidelines severity grading, cholangitis management, ERCP indications, and acute pancreatitis with Revised Atlanta Classification, BISAP score, Ranson criteria, CTSI/Balthazar score, fluid resuscitation, nutrition, and necrotizing pancreatitis management.
ACLS & Cardiac Arrest — Part 2: Cardiac Arrest Algorithms & ACLS Pharmacotherapy
VF/pVT and asystole/PEA algorithms, H's and T's reversible causes, epinephrine, amiodarone, lidocaine, sodium bicarbonate, calcium, magnesium, lipid emulsion, and advanced airway management during arrest.
Traumatic Brain Injury — Part 1: Classification & CT Imaging Decision Rules
GCS scoring, TBI severity classification, Canadian CT Head Rule, New Orleans Criteria, PECARN pediatric head CT algorithm, and comparison of imaging decision rules with sensitivity and specificity data.
Trauma Primary and Secondary Survey — Part 1: Trauma Team Activation & Primary Survey (ABCDE)
Two-tier trauma team activation criteria, CDC field triage, and complete ABCDE primary survey including airway with C-spine protection, breathing and ventilation, circulation with hemorrhage control, disability assessment with GCS, and exposure/environment.
Toxicology and Overdose Management — Part 1: General Approach, Toxidrome Recognition & GI Decontamination
Initial approach to the poisoned patient including toxidrome recognition, diagnostic workup, toxicology screen interpretation, and gastrointestinal decontamination strategies including activated charcoal, whole bowel irrigation, gastric lavage, and multi-dose activated charcoal.
Pediatric Emergencies — Part 1: Pediatric Assessment & Resuscitation (PALS)
Pediatric vital signs by age, pediatric assessment triangle, weight estimation, PALS algorithms for pulseless arrest, bradycardia, and tachycardia, weight-based medication dosing, defibrillation energy, and equipment sizing.
Acute Stroke Management — Part 1: Prehospital Recognition, ED Evaluation & Neuroimaging
Stroke types, prehospital stroke scales (CPSS, LAMS, RACE, FAST-ED), complete NIHSS scoring, focused history, laboratory evaluation, and neuroimaging (NCCT, CTA, CTP, MRI/DWI, ASPECTS).
Acute Pain & Procedural Sedation — Part 1: Pain Assessment & Non-Opioid Analgesics
Pain assessment scales (NRS, VAS, FACES, FLACC, PAINAD), oligoanalgesia prevention, and first-line non-opioid analgesics including acetaminophen, NSAIDs, subdissociative ketamine, IV lidocaine, trigger point injections, and nitrous oxide.
Acute Coronary Syndromes — Part 1: Definitions, Pathophysiology & Initial Evaluation
ACS spectrum definitions, Fourth Universal Definition of MI (Types 1-5), pathophysiology, initial ED evaluation, 12-lead ECG interpretation, STEMI criteria by territory, STEMI equivalents, and right ventricular MI.
Acute Airway Management & RSI — Part 1: Airway Assessment & Preoxygenation
LEMON assessment, Mallampati classification, Cormack-Lehane grading, MOANS/RODS/SHORT mnemonics, 3-3-2 rule, standard preoxygenation, HFNC apneic oxygenation, NIV preoxygenation, and optimal patient positioning.
Acute Abdominal Emergencies — Part 1: Systematic Approach to Acute Abdominal Pain & Appendicitis
Structured approach to acute abdominal pain evaluation including history, physical exam, differential diagnosis by pain location, laboratory and imaging strategy, and comprehensive appendicitis management with Alvarado score, AIR score, and CODA trial evidence.
ACLS & Cardiac Arrest — Part 1: BLS Foundation, High-Quality CPR & Defibrillation
Chain of survival, high-quality CPR parameters, compression-only CPR, AED use, manual defibrillation energy levels, pad placement, waveform capnography, and refractory VF strategies.